He lineweaver–burk plot, which plots the reciprocal of the reaction rate (1/v) versus the reciprocal of the substrate concentration (1/[s]), is a graphical representation of enzyme kinetics. this plot is typically used to determine the maximum rate, vmax, and the michaelis constant, km, which can be gleaned from the intercepts and slope. identify each intercept and the slope in terms of the constants vmax and km.