Chemistry, 28.09.2019 03:30 garyyunga2002

Draw and briefly explain the log-dose response curve and the corresponding lineweaver-burke plot for:

a) morphine alone and together with naloxone

b) buprenorphine alone and together with naloxone

the curves do not have to be based on the actual ed50 values for the compounds. instead, you have to research how each of the compounds behave at the µ-opioid receptor (i. e. full or partial agonist, competitive or non-competitive antagonist, make sure to cite your references). based on this information you should draw hypothetical curves for morphine and buprenorphine alone and if given together with naloxone.

if you need more information, let me know what data you are looking for and i will certainly provide. the curves do not have to be based on the actual ed50 values for the compounds.

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Draw and briefly explain the log-dose response curve and the corresponding lineweaver-burke plot for...