An enzymatic reaction (e+s2 es> p +e) obeys michaelis-menten kinetics and gave the following 4. kinetic results: k1 = 1.0 × 108 m-1 s-1, k-1 = 1.0 × 103 s-1, k2 = 1.0 × 104 s-1 e1-e+est-1.0 x10-6m a. what is the dissociation en b. what is km for the enzyme? c. what is the turnover number (kcat) for the enzyme? d. what is the catalytic efficiency (kak? e. what is a typical value of a bimolecular diffusion limited rate constant and how does it compare with constant (k-61) for the enzyme-substrate complex? [ejis [es f. what is the value of vmax? g. what concentration of substrate would give a reaction velocity (v) equal to 0.75*vmax? h. if the initial substrate concentration ([slo) is equal to 10.0 mm and initial product concentration is zero, how long will it take to form a product concentration of 4.0 mm? state any assumptions. if the initial substrate concentration is reduced to 10.0 nm and initial product concentration is zero, how long will it take to form 4.0 nm product? state any assumptions. i.

when—without warning—something provokes your anger, you may struggle not to succumb to it. since what typically makes you mad is feeling powerless in the face of what seems unfair, your anger is mostly an attempt at a “quick fix” to right the balance. it’s as though you’re raising a fist in protest, proclaiming that you’re not going to capitulate to such injustice.

there are, however, a multitude of problems related to this immediate, push-back reaction of anger. and probably the key one is that almost never does it resolve the issue that gave rise to it. such reactive anger is probably best understood as self-defeating. as david burns, the author of the seminal self- book feeling good, observes: if realistically, acting on your anger is to make any sense, it needs to meet two criteria—which, in almost every case, is frankly impossible. that is, your anger must:

be directed toward a person who has intentionally (and needlessly) behaved in a hurtful way toward you; and

be beneficial or advantageous to you (i.e., assist you in achieving a desired goal).

i think you’ll agree that only rarely can you claim that your anger is both warranted and , whether to yourself or the relationship.

so let me offer you a two-step alternative to abandoning your better judgment and giving in to the temptation of anger—one that should neutralize your anger in seconds. or, when you’re really angry, in minutes.

but keep in mind that you must really want to execute these steps, be sufficiently motivated to perform them. which means overcoming more unconscious resistance than you might ever have imagined. because there are many immediate “advantages” of anger that can interfere with your resolve, i’ll suggest a few of them that might interfere with your employing this powerful method to rid yourself of counter-productive anger.

explanation:

20 drops hope this