Pamela's immune system has been destroyed, leaving her body unable to fight disease and vulnerable to a variety of opportunistic infections and cancers. pamela has which started as

Pamela has Acquired Immunodeficiency syndrome (AIDS) 

Acquired Immunodeficiency syndrome (AIDS) is a diseases that breakdown the immune system in which the body is unable to fight off any form infection that might attack the body. Thus, the infection that attack the body when the immune system is weak can be refers to as opportunistic infections.