What is the next step in the process after a substrate enters the active site of an enzyme?

Enzymes are biocatalysts which increases the rate of the biochemical reaction by lowering the activation energy of the reaction.

It performs the catalysis in four steps:

Thus, the correct answer would be the formation of the enzyme-substrate complex.

this protocol provides a detailed procedure for chromatin immunoprecipitation (chip) to study the dna-protein interactions.

a "theory" a suggestion that is not 100 % accurate, or a figure. some people say its a theory because they of all the passed theory's about one subject. it depends sometimes theory might be accurate and sometimes they are.