Each strand of a dna molecule can act as a template for dna replication because each strand of a dna molecule can act as a template for dna replication because the rules of complementary base pairing dictate exactly what the sequence of nucleotides in a newly synthesized strand should be. your entire genome sequence is stored in your brain, and your brain tells each copy of the dna polymerase enzyme what to do. the two strands of a dna molecule are exactly the same. the two chromosomes in a homologous pair are identical to each other. genes that are read during transcription may be found in either strand of the dna molecule.