If huntington's disease is due to a dominant trait, shouldn't three-fourths of the population have huntington's while one-fourth has the normal phenotype? in large populations, mendelian ratios are ineffective. appearance of a trait in a population does not solely depend on its dominant or recessive nature. natural selection is eliminating huntington’s disease.

Appearance of a trait in a population does not solely depend on its dominant or recessive nature.

Explanation:

The appearance of a trait in a population is not only dependent on its dominant or recessive nature.

Huntington's disease is caused by a mutation in the gene that encodes a protein called huntingtin (Htt). This mutation produces an altered form of the Htt protein, which causes the death of nerve cells (neurons) in certain brain regions. Even if caused by a dominant gene, Huntington's disease will only be expressed in 50% of people who inherit this gene from their parents. This will depend on the organism's gene expression and other factors besides the dominant character of this gene.