A. histamine released from mast cells causes relaxation of smooth muscle in the walls of capillaries, which increases local blood flow. b. during inflammation, plasma proteins leak into the extravascular space, increasing the rate at which water leaves capillaries by osmosis. c. delivery of oxygen and nutrients is aided by increased fluid flow through inflamed areas. d. neutrophils accumulate in the extravascular space in inflamed areas. e. both basophils and mast cells are granulocytes.