Why is it important to cut thin tissue samples with a microtome?.

A microtome is used to make thin slices of tissue (usually 4 μm but can be 2–10 μm). The cut tissue is floated over a water bath, to eliminate wrinkles and distortion in the tissue, and picked up on a slide.

in 1972 the fluid—mosaic membrane model of membrane structure was proposed based on thermodynamic principals of organization of membrane lipids and proteins and available evidence of asymmetry and lateral mobility within the membrane matrix [s. j. singer and g. l. nicolson, science 175 (1972) 720–731].