Before cell division start the DNA must be. Plz help

Which term most precisely describes the cellular process of breaking down large molecules into smaller ones? a) catalysis b) metabolism c) anabolism d) dehydration e) catabolism

During crossing-over, a. genetic material is exchanged between nonsister chromatids, resulting in new combinations of alleles. b. nonsister chromatids from each homologous chromosome of a tetrad are exchanged, resulting in new combinations of alleles. c. one homologous chromosome of a tetrad is exchanged with another tetrad, resulting in new combinations of alleles. d. sister chromatids from each homologous chromosome of a tetrad are exchanged, resulting in new combinations of alleles. e. genetic material is exchanged between sister chromatids, resulting in new combinations of alleles.

Which factor is difficult to assess in a cost-benefit analysis