Which of the following statements about genes and alleles are true?1. Qualitative traits are each determined by a single gene that has a small number of alleles2. When a gene has 2 alleles, the allele frequency in a population move toward equilibrium values for 0.5 for each allele3. All else being equal, alleles associated with higher reproductive success decrease in frequency4. If the frequency of an allele in a population has changed over generations, then evolution has occured