Biology, 06.09.2021 21:20 jr294

Gluten protein in the diet is broken down in the body to various peptides. One of these peptides is gluten exorphin B4, a peptide with opioid properties possibly associated with autism and schizophrenia. a. The amino acid sequence of gluten exorphin B4 is YGGW. Using simple stick figures, show a titration experiment of the peptide from low to high pH. Clearly indicate the pKa values of the ionizable groups, and the net charge of the different species.
b. What is the isoelectric point of gluten exorphin B4?
c. Gluten exorphins can be detected in the urine (pH ~ 6) of autistic children. Draw the structure of gluten exorphin B4 at pH 6.0. Show correct stereochemistry around the alpha carbon.
d. Gluten exorphin B4 binds the opiate receptor in the brain with KD = 4.1 Î¼M at physiological temperature (37 Â°C). What is the change in free energy for the binding reaction?

Answers: 3

Show answers

Other questions on the subject: Biology

Biology, 22.06.2019 02:30, nstacie40

Astudent reads the following text in a science book: scientific evidence tells us that the cause of earths four seasons is the tilt of earth as it revolves around the sound the student is instructed to illustrate this information in a science book. how will the student illustrate winter in the northern hemisphere? a. earths northern hemisphere will tilt away from the sun. b. earths northern hemisphere will tilt toward the sun. c. earths orbit will be farther away than from the sun d. earths southern hemisphere will tilt away from the sun.

Answers: 1

continue

Biology, 22.06.2019 03:50, kony345p

Which statement about the pancreas is not true? a. it is an endocrine organ in the abdomen. b. it release chemicals into the digestive system. c. it releases insulin to increase glucose levels. d. it release hormones into the bloodstream.

Answers: 1

continue

Biology, 22.06.2019 05:30, staffordkimberly

Where can a dna be found in a prokaryotic cell

Answers: 1

continue

Biology, 22.06.2019 11:30, gymnastcaitlyn1

There are multiple lines of evidence that provide support for common ancestry and evolution. write 3-4 paragraphs describing at least three of them in detail. provide at least one example for each line of evidence.

Answers: 1

continue

You know the right answer?

Gluten protein in the diet is broken down in the body to various peptides. One of these peptides is...