Gluten protein in the diet is broken down in the body to various peptides. One of these peptides is gluten exorphin B4, a peptide with opioid properties possibly associated with autism and schizophrenia. a. The amino acid sequence of gluten exorphin B4 is YGGW. Using simple stick figures, show a titration experiment of the peptide from low to high pH. Clearly indicate the pKa values of the ionizable groups, and the net charge of the different species.
b. What is the isoelectric point of gluten exorphin B4?
c. Gluten exorphins can be detected in the urine (pH ~ 6) of autistic children. Draw the structure of gluten exorphin B4 at pH 6.0. Show correct stereochemistry around the alpha carbon.
d. Gluten exorphin B4 binds the opiate receptor in the brain with KD = 4.1 μM at physiological temperature (37 °C). What is the change in free energy for the binding reaction?

bru what tyep of qus is dis

1. amino acid refers to the fundamental building block of proteins, comprising of an amino group and a carboxyl group.

2. catalyst refers to any substance, which increases the rate of chemical reaction without being used up in the reaction.

3. a complex molecule containing he genetic code is dna or deoxyribonucleic acid.

4. an enzyme refers to a molecule of protein, which is unique in accelerating up a particular chemical reaction in the biological systems.

5. nucleic acid refers to an sequence of sugars, phosphates, and nitrogenous bases, for example, dna and rna.

6. a protein refers to a large, composite organic molecule comprising of a huge number of amino acids associated together with the of peptide bonds.

7. rna refers to a nucleic acid that takes part in the production of proteins.

8. substrate refers to a compound, which takes part in a chemical reaction, and is chemically modified by the reaction.