Why the plasma membrane is impermeable to many types of substances?

The membrane is selectively permeable because substances do not cross it indiscriminately. Some molecules, such as hydrocarbons and oxygen can cross the membrane. Many large molecules (such as glucose and other sugars) cannot. Water can pass through between the lipids

Explanation:

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they had the law tat factories that produces smoke cannot be built near residential buildings.

building of proper sewage system was done to ensure that the waste is carried away from the humans so that they do not get diseases from it.

also they built water systems to provide water in those areas which are drought prone.