Why does alcohol abuse increase tolerance to other drugs such as barbiturates?

Alcohol abuse increase tolerance to other drugs because:
Alcohol and other drugs such as barbiturates (drug used for central nervous system depressant) induce proliferation of smooth endoplasmic reticulum. These are associated with detoxification of enzymes and it will increase the rate of detoxification. 

Answer:

1: the largest region of the brain is the:

  cerebrum

2. the term "psychology" literally means:

the process or procedure of the science or study of the mind.

3. the area of the brain responsible for respiration, heart rate, and smooth muscle control of our blood vessels is t

medulla oblongata

4. the structure that conducts nerve impulses to and from the brain and serves as a reflex center for some sensory information without input from the brain is the:

spinal cord

5. the three-layered membrane that covers the brain and spinal cord and literally means membrane is called the:

meninges

6. the cord-like (string-like) structures that carry bio-electrical impulses from one part of the body to another are called

nerves

7. a group of nerve cell bodies that are found outside of the spinal cord and brain are referred to as:

ganglions or ganglia (pl.) “literal meaning knot”

8. the term that means spinal cord inflammation is:

myel/itis

They are all in a iving organism.