The major anatomical difference between gray matter and white matter is the major anatomical difference between gray matter and white matter is that white matter is primarily in the cns the presence of myelinated axons that white matter is located deep to the gray matter that gray matter is functionally organized into tracts

Our central nervous system is made up of two tissues: the gray matter and the white matter. The gray matter is composed of the dendrites and the axon terminals where synapses are. These synapses are the links between neurons that transmits electrochemical signals. The white matter, on the other hand, is composed of axons that connect all the gray matter together. Therefore, the answer is: white matter is primarily in the CNS in the presence of myelinated axons

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