What type of mutation has occurred in the dna of people with sickle cell anemia? (look back, if you need to, to see what causes sickle

People with two copies of the sickle cell gene have the disease. People who carry only one copy of the sickle cell gene do not have the disease, but may pass the gene on to their children. Abnormal hemoglobin, called hemoglobin S, causes sickle cell disease (SCD). The problem in hemoglobin S is caused by a small defect in the gene that directs the production of the beta globin part of hemoglobin. This small defect in the beta globin gene causes a problem in the beta globin part of hemoglobin, changing the way that hemoglobin works.