What proteins are crucial for creating and maintaining dna replication forks?

Helicases unwind the two parental DNA’s strands and creates the replication fork; single strand binding proteins keep the single strand from joining.

Further information:

•DNA replication: a biological method occurring in all living organisms that is the basis for biological inheritance

•Helicase: It is an enzyme that may unwinds the DNA helix ahead of the replication machinery.

•Origin of replication: a specific sequence in a genome at which replication is started.

Steps of DNA replication:

• During initiation, proteins fix to the source of replication while helicase unwinds the DNA helix and two replication forks are formed at the source of replication.

•During elongation, a primer sequence is added with complementary RNA nucleotides, which are then substituted by DNA nucleotides.

•During elongation the leading strand is made constantly, while the lagging strand is made in portions called Okazaki fragments.

•During termination, primers are detached and substituted with new DNA nucleotides and the backbone is stuck down by DNA ligase.

Purpose of DNA replication:

The purpose of DNA replication is to produce two duplicate copies of a DNA molecule. This is essential for cell division during development or repair of damaged tissues. DNA replication ensures that each new cell receives its own replica of the DNA.

Answer details:

Subject: Biology

Level: High school

Keywords:

•DNA replication

•Helicase

•Origin of replication

•Steps of DNA replication

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