The virulence factor associated with the events of gram negative sepsis and septic shock is

There are many factors associated with the events of gram negative sepsis and septic shock such as risk factors for organ dysfunction, infection, contingent upon developing infection.  Other factors include residence in care facilities for long time, use of immunosuppressive medications, prosthetic devices, and malnutrition.

white blood cells or wbc s are mainly 2 types-

1.agranulocytes

2.granulocytes

the monocytes or macrophages of agranulocytes , dendritic cells which are accessory leucocytes, and b cells which is one type of lymphocytes   identify the antigens present on the pathogen's surface. these three cells are called antigen presenting cells(apc) which are phagocytes and destroy the antigens by secreting antitoxins. besides this leukocyte is always plays vital role in the immunity of the body.

during the process of dna replication, brdu can replace thymidine and incorporate into the newly synthesized dna, cell proliferation thus can be reflected in the extent of brdu incorporation.