If spontaneous generation does not occur and the principle of biogenesis is true - what scientific question remains unanswered

It is the Unanswered questions concerning the Big Bang: 

1) What drove the initial expansion of space? 
2) Why did inflation stop? 
3) What existed before the start of expansion? And does the word "before" have any meaning if there is no time?

When you are making a guess you are forming a hypothesis

When a virus infects a host cell, it uses the cell's machinery to make copies of its own genetic material in a process called replication. finally, during the process of self-assembly, that protein shell and the copies of the virus's genetic material are assembled into new viruses.