What happens when a nucleotide pairs with the wrong nitrogen base? dna polymerase pauses the process of dna replication and initiates a series of steps to correct the problem. primase sets down an rna primer that initiates a sequence of events to correct the error. a single nucleotide error is not a problem, so the cell does not have a process to change it. it is simply left in place. okazaki fragments are formed and inserted to make the correction.