"what must occur before a newly made polypeptide is secreted from a cell?

a. it must be translated by a ribosome that remains free within the cytosol

b. its signal sequence must target it to the er, after which it goes to the golgi

c. its signal must be cleaved off before the polypeptide can be enter the er

d. its signal sequence must target it to plasma membrane, where it causes exocytosis

Choose the incorrect statement (a) the motor end plate membrane is only capable of generating graded potentials, but it is contiguous with the skeletal muscle sarcolemma, which can generate action potentials. (b) propagation of an action potential through the t-tubules into the sarcoplasmic reticulum triggers the release of ca++ into the cytoplasm of a skeletal muscle fiber. (c) the generation of suprathreshold endplate potentials in multiple muscle fibers could be due to the increased frequency of action potential generation at the axon hillock of a single motor neuron. (d) a greater amount of ach would be found in the presynaptic vesicles of a motor unit that fired several action potentials after exposure to botulinum toxin, than in a motor unit that fired several action potentials after exposure to the venom of the krait snake (which contains α-bungarotoxin).