Biology, 05.10.2019 06:30 neverfnmind

What is the difference between t dependent antigen and t independent antigen?

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The non-protein microbial antigens can not stimulate classical T cell response by themselves, but they are able to elicit the production of antibodies, so that is why we call them T or thymus independent antigens. T independent antigens are divided into 2 classes by the mechanism of activating B cells. TI-1 antigen.

For most protein antigens, the production of antibodies by B lymphocytes isdependent on stimulation of helper T cells. However bacterial polysaccharides and lipopolysaccharides, and some polymeric proteins, can stimulate B lymphocytes without involvement of helper T cells.

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Answer from: Quest

you are certainly talking about this picture:

a: is the label of the white square, it is showing the replication fork, formed by helicase (d) ==> so it is the site of dna separation and replication

b: is a new dna brand that is following directly the replication fork, so it is continuous ==> built continuously from 5' to 3

c: dna polymerase cannot replicate dna on its own, it needs the of their proteins, and one of them plays the role of a clamp which fixes the dna with the dna template and increases the processivity of the enzyme. ==> stops polymerase from falling off the template.

d: is the enzyme responsible for forming the replication fork (helicase) ==> unwinds and separates dna into two strands

e: is the delayed strand, it is built in the opposite sense of the helicase, so dna will be built in fragments ==> built fragments from 5' to 3 joins

and finally f: is the enzyme that builds the new dna strand (dna polymerase) ==> adds nucleotides to make a new dna helix.

credit: gradman555p98x9p

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