Indicate whether the C-terminus (C) or the N-terminus (N) of each of the following proteins is expected to be located in the cytosol upon membrane integration of the protein. Your answer would be a three-letter string composed of letters C and N only, e. g. CCC. (A) A single-pass transmembrane protein that has one N-terminal signal sequence and one internal stop-transfer signal
(B) A single-pass transmembrane protein that has one internal signal sequence that is preceded by a patch of positively charged residues
(C) An ER tail-anchored protein

The correct answer is - CNN.

Explanation:  

Protein modification or folding takes place in the endoplasmic reticulum. The Endoplasmic Reticulum modifies the amino acids according to their signal sequences and tail. The following case can help in indicating the C-terminus (C) or the N-terminus (N) of each of the following proteins-

A) the C-terminus would be placed in the cytosol and the N-terminus in the endoplasmic reticulum lumen after cleaving the N-terminal signal sequence.

B) The N -terminal is the positive end of the chain and as per the rule of positive inside it allows N terminal in the cytosol

( C ) Tail-anchored proteins always have their N-terminal bulk in the cytosol.

Thus, CNN would be the correct answer from the explanation given above.

the correct answer should be false

{apex}

1. amino acid refers to the fundamental building block of proteins, comprising of an amino group and a carboxyl group.

2. catalyst refers to any substance, which increases the rate of chemical reaction without being used up in the reaction.

3. a complex molecule containing he genetic code is dna or deoxyribonucleic acid.

4. an enzyme refers to a molecule of protein, which is unique in accelerating up a particular chemical reaction in the biological systems.

5. nucleic acid refers to an sequence of sugars, phosphates, and nitrogenous bases, for example, dna and rna.

6. a protein refers to a large, composite organic molecule comprising of a huge number of amino acids associated together with the of peptide bonds.

7. rna refers to a nucleic acid that takes part in the production of proteins.

8. substrate refers to a compound, which takes part in a chemical reaction, and is chemically modified by the reaction.