What is the primary mechanism associated with the role of fluoride in prevention of dental caries?​ a. ​Fluoride increases calcium absorption, which increases crystal formation of teeth b. ​Fluoride increases salivation which aids in the removal of bacteria and the foods needed to sustain bacterial growth c. ​Decay is reduced due to the inhibitory effects of fluoride on growth of bacteria on the teeth d. ​Fluoride becomes incorporated into the crystalline structure of teeth, making them less susceptible to decay e. ​Decay is inhibited due to neutralization of organic acids produced by bacteria on the teeth

d. ​Fluoride becomes incorporated into the crystalline structure of teeth, making them less susceptible to decay

Explanation:

Dental caries results when cariogenic (caries-causing) bacteria metabolize carbohydrates or sugars present in the mouth for their energy needs, producing organic acids as byproducts, thus lowering the pH of the plaque biofilm.

The hydroxyapatite of tooth enamel is composed mainly of phosphate ions (PO₄³⁻) and calcium ions (Ca⁺). Under normal conditions, there is a stable equilibrium between the calcium and phosphate ions in saliva and the crystalline hydroxyapatite. At low pH (acidic conditions), there is a shift in equilibrium resulting in the dissolution of hydroxyapatite from tooth enamel, a process known as demineralization. A reverse process called remineralization (the process of incorporation of minerals in tooth enamel) occurs when the saliva, acting as a buffer elevates pH. When equilibrium is shifted to favor continued demineralization, dental caries results.

However, when fluoride is present in saliva, fluorapatite, rather than hydroxyapatite, forms during the remineralization process as fluoride ions replace hydroxyl groups in the formation of the apatite crystal lattice.

Fluorapatite is less soluble than hydroxyapatite making it more resistant to demineralization, even under conditions of low pH. Thus, fluoride acts as an effective anticaries agent.

hormones in blood stream

image: dtc.ucsf.edu

endocrine glands secrete hormones into the blood stream near them; the hormones then travel in our bloodstream until it reaches its destination, called a target cell, in distance parts of the body. in the target tissue, hormones lock onto the target’s plasma membrane, called the receptor site.

you are certainly talking about this picture:

a: is the label of the white square, it is showing the  replication fork, formed by helicase (d) ==> so it is the site of dna separation and replication 

b: is a new dna brand that is following directly the replication fork, so it is continuous ==> built continuously from 5' to 3

c: dna polymerase cannot replicate dna on its own, it needs the of their proteins, and one of them plays the role of a clamp which fixes  the dna with the dna template and increases  the processivity of the enzyme. ==>   stops polymerase from falling off the  template.

d: is the enzyme responsible for forming the replication fork (helicase) ==> unwinds and separates dna into two strands

e: is the delayed strand, it is built  in the opposite sense of the helicase, so dna will be built in fragments ==> built  fragments from 5' to 3 joins

and finally f: is the enzyme that builds  the new dna strand (dna polymerase) ==>   adds nucleotides to make a new dna helix.

credit: gradman555p98x9p

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