Which of the following uses of genetically modified organisms would cause the greatest concern to the public? Group of answer choices

A gene is transferred into to the DNA of a plant, enabling it to produce a toxin that kills crop eating caterpillars by poisoning their gut.

Incorporating recombinant DNA into plasmids so that bacteria produce insulin for patients with diabetes.

Using gene therapy to replace defective genes in patients with sickle cell anemia.

Recombinant DNA being used to enable a bird flu to transfer from human to human in order to study the genetics of human to human transfer