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Prokaryote: lack of membrane-bound nucleus, DNA in cytoplasm, single circular chromosome

Eukaryote: Membrabe-bound nucleus, DNA inside nucleus, multiple chromosome.

Explanation:

Prokaryotes are one of the two domains, which consists of organisms that do not possess a membrane-bound nucleus. Due to this fact, the genetic material (DNA) of prokaryotic organisms like bacteria is found located in their cytoplasm. The DNA is found as a single circular chromosome in a region called NUCLEOID.

On the contrary, eukaryotes are the second domains of organism characterized by their possession of a membrane-bound nucleus that houses their genetic material (DNA). All the DNA of an eukaryotic organism like plants, animals etc. are found inside its NUCLEUS. They are made up of multiple linear chromosomes.

a.) a destruction fo cells by viral reproduction