There are no known motor proteins that move on intermediate filaments (IFs). What property of intermediate filaments would most likely explain the lack of motor proteins?
a) Tissue specific expression of IFs prevent a single type of motor protein to evolve over time.
b) Lateral bundling of IFs prevent motor movement.
c) IFs do not bind a nucleotide.
d) IFs are less dynamic than microtubules and actin filaments.
e) IFs are unpolarized.

The correct option is E ( Intermediate filaments are unpolarized).

Explanation:

Intermediate Filaments are usually associated with cells that can withstand mechanical stress which includes claws of animals, hair and makes up the dead remnants of the epidermal cell of the skin. Therefore without the supporting network of intermediate filaments, an epithelium remains intact but the cells are prone to damage by abrasive forces.

Intermediate filaments are so named because they are thicker than actin filaments and thinner than microtubules or muscle myosin filaments

The properties or characteristics of an intermediate filaments that explains the lack of motor proteins is as a result of its subunits which are elongated, not globular and are associated in an anti-polar manner. Therefore, the overall filament has no polarity, and therefore no motor proteins move along intermediate filaments

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