Biology, 20.11.2020 07:00 lilyplant4289

Nuclear hormone receptors form a complex with their ligands, other proteins, and DNA control elements in order to regulate the expression of specific genes. These nuclear hormone receptors have four principal domains. Categorize each trait according to the appropriate nuclear hormone receptor domain with which it is associated. Domains:
amino-terminal activation domain
DNA binding domain
hinge domain
ligand-binding domain

Traits:
1) binds coactivators
2) carboxyl-terminal end
3 )center of receptor
4) 9 conserved cysteine residues
5) zinc-finger domain
6) nuclear localization signal
7) AF2 activation domain
8) steroid-binding hydrophobic pocket
9) binding of corepressor proteins

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interphase

the period of cell growth when the cell synthesizes new molecules and organelles. the cell is not dividing and it constitutes the majority of the time spent in the cell cycle

prophase

changes occur in the nucleus and cytoplasm. the chromatin condenses to form structures (sister chromatids) visible with a light microscope and the mitotic spindle begins to form, but the nucleus is still in tact

prometaphase

the nuclear envelope fragments and the spindle microtubules attach to the kinetochores of the sister chromatids

metaphase

all the cell's duplicated chromosomes are lined up at an imaginary plane equidistant between the poles of the mitotic spindle

anaphase

begins when sister chromatids separate from each other and ending when a complete set of daughter chromosomes arrives at each of the two poles of the cell

telophase

the daughter nuclei form at the two poles of a cell

cytokinesis

the division of a cytoplasm to form two separate daughter cells. usually occurs during telophase during mitosis. this and mitosis make up to mitotic (m) phase of the cell cycle

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In order to understand the problems of unwanted infertility in a country — the gambia — where the desire for children and the fertility is very high, a population-based survey was undertaken. all infertile women in 24 randomly selected enumeration areas were assessed. the study included a review of the problems faced and coping mechanisms employed by infertility clients and types of health care available for infertile couples in the different types and levels of the formal and traditional health system. half of the infertile couples failed to seek formal health care, and they have to reach a certain level of care in order to be properly managed. alternative care is often sought. child fostering is also a frequent solution to childlessness. in-depth interviews revealed that traditional care like healers and spiritual leaders are frequently consulted long before formal health care. this delay could be a problem in those cases where infertility is caused by infections.