THE MOLECULAR GENETICS OF CYSTIC FIBROSIS
The following is the base sequence of DNA that codes for amino acids 506-510 of the protein that
regulates the chlorine channels in the cell membrane. This protein contains a total of 1476 amino
acids so this is a small part of the entire gene.
DNA Template Strand:
3'TAGTAGAAACCACAA5'
1. What is the minimum number of DNA nucleotides in this whole gene?
the strand of DNA that is complementary to the template
2. What is the sequence of bases
strand?
3. What mRNA will be formed from the template strand of DNA?|
4. What amino acids will this mRNA code for?
5. If the 6th, 7th and 8th bases in the template strand of the DNA are removed, rewrite the new
template strand below.
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THE MOLECULAR GENETICS OF CYSTIC FIBROSIS
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