Which of the following are functions related to the expression of MHC molecules? a. To display self-peptides to test developing T cells for autoreactivity
b. To display self-peptides to demonstrate cell health
c. To display self-peptides to maintain self-tolerances
d. To display foreign peptides
e. All of the answers are correct.

e. All of the answers are correct.

Explanation:

The major histocompatibility complex (MHC) is a locus that contains several polymorphic genes. These genes are known to encode different components of the immune system, especially cell-surface proteins which present antigens to the T cell receptors during adaptive immune responses. The MHC genes are classified into Class I, Class II and Class III:

1- MHC class I genes encode cell surface molecules that present peptides (antigens) to cytotoxic T lymphocytes (i.e., killer T cells)

2- MHC class II genes encode cell surface molecules that present antigens to CD4+ T cells

3- MHC class III genes encode proteins that are not involved in antigen presentation (i.e., components of the complement cascade, cytokines, etc)

the glands which are associated with each description is given below: