What 2 things must pass out of the nuclear pores?

The two things that must pass through nuclear pores are small polar molecules, ions, and macromolecules (proteins and RNAs)

Explanation:

carbohydrates: (starches and sugars) composed of carbon, hydrogen, and oxygen.

lipids: (fats, oils, and waxes) are made of carbon and hydrogen atoms.

nucleic acids: contain hydrogen, oxygen, nitrogen, carbon, and phosphorus. they are polymers of nucleotides. a nucleotide has three parts, a 5-carbon sugar, a phosphate     (-po⬇️4) group, and a nitrogenous base.

proteins: made up of nitrogen, carbon, hydrogen, and oxygen. they are polymers of amino acids.