TRBP is a protein important for the formation of the RISC complex. Which of the following would you expect in cells with null mutations in TRBP? a. Reduced siRNA-mediated mRNA degradation
b. Increased miRNA-mediated translational repression
c. Increased deadenylase-mediated mRNA degradation
d. Reduced proteasome-mediated protein degradation

a. Reduced siRNA-mediated mRNA degradation

Explanation:

The TRBP (transactivation response element RNA-binding protein) is an RNA-binding protein that forms the Dicer complex, which is involved in epigenetic pathways such as those mediated by the RNA interference (RNAi) mechanism. RNAi is a key process where small non-coding RNAs such as, for example, small interfering RNAs (siRNAs) and microRNAs (miRNAs) can inhibit target gene expression at posttranscriptional level by different mechanisms (including the degradation of target mRNAs). A null mutation of this cofactor will alter the Dicer complex, thereby also affecting RNAi pathways mediated by small interfering RNAs.

its been noted for the past decade or so that there is some (approximately 5% to 7%) shrinkage in the brains of people who have schizophrenia, most notably in the gray matter, which is an important part structures in the brain’s amygdala, hippocampus and parahippocampus, which are all involved in memory storage and retrieval memory storage and retrieval.

explanation:

ive read articles

c. movement because i took the test and it lets me review my answers