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Biology, 04.07.2020 19:01 Juniper816

In the nematode roundworm, Caenorhabditis elegans, the LIN-14 protein controls the timing of certain cell divisions during development. LIN-14 protein levels are normally high in early development but decrease in the later stages. In a lin-4 mutant, the level of LIN-14 protein stays high throughout development, changing the pattern of cell divisions in the animal and producing defects in the shape of the animal. The lin-4 gene encodes a microRNA that binds to a sequence in the 3' UTR of the lin-14 mRNA. Required:How does the lin-4microRNA likely regulate LIN-14 protein levels? Explain why the lin-4mutant has high levels of LIN-14 throughout development.

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In the nematode roundworm, Caenorhabditis elegans, the LIN-14 protein controls the timing of certain...

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