Biology, 06.06.2020 21:00 preety5445

Older Affected brother child DNAse l is an enzyme that cleaves DNA accessible to it. When chromatin is remodeled during active gene transcription, regulatory DNA becomes accessible to cleavage by DNAse I. In contrast, the regulatory DNA of genes not being actively transcribed is resistant to DNAse I induced cleavage. You obtain DNA from the affected child and her older brother and treat both samples with DNAse I. With the treated DNA, you separate DNA fragments with gel electrophoresis, blot the DNA to a membrane, and probe the membrane with a DNA probe that spans the entire gene along with some flanking DNA Your results are shown in this gel. What can you conclude from these results?

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Older Affected brother child DNAse l is an enzyme that cleaves DNA accessible to it. When chromatin...