A genetic change that occurs in a body cell of a mouse will not contribute to the evolution of the species because

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Explanation:

a genetic change that occurs in a body cell of a mouse will not contribute to the evolution of the species because genetic changes that occur to the somatic cells of organisms are are not passed to the next generation.

Evolution generally involves a gradual change to organisms over a long period of time. Mutation, on the other hands, refers to changes to the genetic components of organisms.

Mutations that happen to the somatic cells of organisms are referred to as somatic mutations while those that happens at the germ-line levels of organisms are referred as germ-line mutations.

While the former are not heritable by offspring, the latter are heritable.  Attributes that cannot be passed to the offspring do not contribute to the evolution of organisms.

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enzyme active site and substrate specificity

enzymes bind with chemical reactants called substrates. there may be one or more substrates for each type of enzyme, depending on the particular chemical reaction. in some reactions, a single-reactant substrate is broken down into multiple products