Which two factors could lead to the evolution of a species over time?

enzyme active site and substrate specificity

enzymes bind with chemical reactants called substrates. there may be one or more substrates for each type of enzyme, depending on the particular chemical reaction. in some reactions, a single-reactant substrate is broken down into multiple products

where in your body is there an enzyme that does function at a high or low ph? what is the name of that enzyme and its function?