How does the population of humans affect orcas

I'm guessing all the waste that goes to the ocean can harm them

toxic exposure, surface impacts, and underwater noise

toxic exposure (pollution), surface impacts (fishing, boating), and underwater noise because Orcas communicate with each other over short and long distances with a variety of clicks, chirps, squeaks and whistles, along with using echolocation to locate prey and to navigate. They may also rely on passive listening as a primary sensory source.

"1. it should be, it has been for about 20 years, and it's really not much different in the end than breeding animals to have particular traits. there are always concerns about genetically engineered animals/plants affecting the environment in unexpected negative ways, but i can't think of an example where the fears didn't turn out to be baseless.  

first, as you point out, it would be a great advance in pharmacology, to be able to tailor drugs and their doses to me. the pros involve better medical treatment. the cons involve privacy issues like insurance companies denying coverage to people with genetic risk factors. looking at dna markers wouldn't affect the frequency of genetic diseases, but it would allow detection of them earlier. and ok, actually i suppose that if people used this information to avoid having children with genetic diseases, some might decrease in frequency."