Sort the following events to reflect the normal order in which they occur in G-protein-coupled receptor signaling leading to transcription of genes with cAMP response elements (CRE). Your answer would be a four-letter string composed of numbers 1 to 4 only, e. g. 1-2-3-4.

(1) Phosphorylation of CREB (CRE-binding protein) by PKA;
(2) Activation of PKA;
(3) The catalytic subunits of PKA enter the nucleus;
(4) Activation of adenylyl cyclase;"

What is the difference between sex-linked traits and autosomal traits in humans? a. sex-linked traits can only be passed from fathers to sons, while autosomal traits can be passed on from both parents to offspring of any sex. b. sex-linked traits are passed on through the x and y chromosomes, while autosomal traits are passed on through the other 22 chromosomes. c. sex-linked traits only affect females, while autosomal traits affect both males and females. d. sex-linked traits refer to genes that are on the x and y chromosomes, while autosomal traits refer to genes on all 23 chromosomes.