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Biology, 22.04.2020 21:59 prettyluhangel

Can antibody diversity in humans be explained solely by V(D)J recombination? Why or why not?Several proteins must work in a coordinating fashion to achieve V(D)J recombination. Which is responsible for adding nontemplated nucleotides to the V-D and D-J joints of Ig heavy chains?Recognition spacer sequences are separated by how many base pairs?If a given B cell is found to be potentially reactive to self-antigens, can the cell make an effort to correct that flaw, or is it destined for eventual removal by apoptosis?

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