What determines whether two proteins will bind to each other? What determines whether two proteins will bind to each other? They will bind to each other if they have complementary shapes and chemical properties. They will bind to each other if they are located in the same region of the cell. They will bind to each other if they are identical or similar proteins. They will bind to each other if one protein has an overall positive charge and one protein has an overall negative charge.

Two proteins will bind to each other if they have complementary shapes and chemical properties.

Explanation:

The study of the molecular structure of proteins gives details about the interface that enable interaction between proteins. These parameters includes the size, shape, complementarity between surfaces, residue interface properties, hydrophobicity, segmentation and secondary structure, and conformational changes on complex formation.

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