Some bacteria have developed a resistance to antibiotics through random mutations. One such mutation allows bacteria to produce enzymes that inactivate the
antibiotics when they enter the bacteria
Which statement describes how this mutation occurs?

1. The nutation occurs when nucleic acids are replicated

2. The mutation occurs in chloroplasts during photosynthesis
3. The mutation occurs in mitochondria during cellular respiration
4. The mutation occurs when molecules move across the cell membrane.