Biology, 14.04.2020 21:46 brittanyjacob8
One form of posttranscriptional modification of most eukaryotic RNA transcripts is the addition of a poly-A sequence at the 3' end. The absence of a poly-A sequence leads to rapid degradation of the transcript. Poly-A sequences of various lengths are also added to many prokaryotic RNA transcripts where, instead of promoting stability, they enhance degradation. In both cases, RNA secondary structures, stabilizing proteins, or degrading enzymes interact with poly-A sequences.
Considering the activities of RNAs, what might be the general functions of 3-polyadenylation? Check all that apply.
A. regulation of mRNA association with cellular components, like proteins, lipids, or nucleic acids
B. regulation of mRNA splicing
C. regulation of mRNA transport to the cytoplasm
D. regulation of mRNA proofreading
E. regulation of mRNA longevity
F. regulation of introns' length
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