Spanish influenza is thought to be caused by

The "Spanish" influenza pandemic of 1918–1919, which caused ≈50 million deaths worldwide, remains an ominous warning to public health. Many questions about its origins, its unusual epidemiologic features, and the basis of its pathogenicity remain unanswered. The public health implications of the pandemic therefore remain in doubt even as we now grapple with the feared emergence of a pandemic caused by H5N1 or other virus. However, new information about the 1918 virus is emerging, for example, sequencing of the entire genome from archival autopsy tissues. But, the viral genome alone is unlikely to provide answers to some critical questions. Understanding the 1918 pandemic and its implications for future pandemics requires careful experimentation and in-depth historical analysis.

the father in the first generation probably had the recessive colorblind trait in his x chromosome. if he and his wife both had the colorblind trait, even if she had 1 recessive and 1 dominant, then that trait would be passed on to their kids.

(since you didn't attach the family tree this is just an assumption)

the answer to your question is slate