Define the "two-hit hypothesis" for retinoblastoma. Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Not all terms will be used. ResetHelp both copies sporadic retinoblastoma only one copy hereditary retinoblastoma of one gene must be mutated in order for retinoblastoma to develop. This hypothesis was based on the finding that always affected both eyes, whereas only affected one eye.

Suppose that on a small island off the coast of scotland, 32 percent of the population has blue eyes, which means that these individuals must be homozygous for the blue eye color gene (bb). the only other eye color found on the island is brown, and individuals that are homozygous for the brown eye color gene (bb) or heterozygous (bb) will have brown eyes because brown is the dominant gene. assume this population is in hardy-weinberg equilibrium. if 100 babies are born next year, how many of these would you expect to have brown eyes and be heterozygous? a. 58 b. 49 c. 29 d. 43