You have discovered a new gene that encodes an unusual regulatory subunit of PKA, which you name Ro. As with the R2C2 version of PKA, Ro forms a dimer and interacts with two molecules of the same catalytic subunit (C) found in PKA to form a Ro2C2 heterotetramer. However, unlike the R in conventional PKA, each Ro subunit binds 8 molecules of cAMP. Which of the following properties would you predict Ro C2 PKA would display compared to the conventional RC2 form of PKA ?a. PKA with Ro subunits would become active at a lower concentration of cAMP. b. Full activity of PKA with Ro subunits would occur at a higher concentration of CAMPc. The dynamic range of activity of PKA with Ro subunits would occur over a narrower range of cAMP concentration. d. The dynamic range of activity of PKA with Ro subunits would over a wider range of cAMP concentration

Compared to the conventional RC2 form of PKA , Ro C2 PKA would display  the following properties :

PKA with Ro subunits would become active at a lower concentration of cAMP.

Full activity of PKA with Ro subunits would occur at a higher concentration of cAMP - Correct Option.

The dynamic range of activity of PKA with Ro subunits would occur over a narrower range of cAMP concentration.

The dynamic range of activity of PKA with Ro subunits would over a wider range of cAMP concentration.

Explanation:

 In the presence of high levels of cAMP the conventional R2C2 form of PKA (R2C2 complex) splits into an R2 subunit and two C subunits. Two cAMP molecules bind to the regulatory sites of the complex. However, each Ro regulatory subunit binds 8 molecules of cAMPin the new gene product . Each regulatory subunit has a distinct binding site for cAMP.  Thus, full activity of PKA with Ro subunits would occur at a higher concentration of cAMP inasmuch cAMP binding to regulatory subunits exhibit positive cooperativity,.

the answer is d. chordata

the oxygenated blood then leaves the lungs through pulmonary veins, which return it to the left heart, completing the pulmonary cycle. this blood then enters the left atrium, which pumps it through the mitral valve into the left ventricle. from the left ventricle, the blood passes through the aortic valve to the aorta.

deoxygenated blood leaves through the right ventricle through the pulmonary artery. from the right atrium, the blood is pumped through the tricuspid valve (or right atrioventricular valve), into the right ventricle.