If administration of a drug is suspected to reduce the alkaline phosphatase level, how would you test for it using a level of signi cance = 0:10: Use the (i) critical value method (ii) p-value method and (iii) con dence interval. Draw proper conclusions in each case.

Yed

Explanation:

A rise in the alkaline phosphatase occurs with all forms of cholestasis, particularly with obstructive jaundice. It is also elevated in diseases of the skeletal system, such as Paget disease, hyperparathyroidism, rickets and osteomalacia, as well as with fractures and malignant tumors. A considerable rise in the alkaline phosphatase activity is sometimes seen in children and juveniles. It is caused by increased osteoblast activity following accelerated bone growth.

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the corpus luteum secretes estrogens and progesterone. the latter hormone causes changes in the uterus that make it more suitable for implantation of the fertilized ovum and the nourishment of the embryo. if the egg is not fertilized, the corpus luteum becomes inactive after 10–14 days, and menstruation occurs.

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