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Biology, 12.03.2020 17:33 bryanmcmillianjr

A. You are performing experiments with your protein of interest and its ligand. You are attempting to mutate the binding site of your protein to disrupt binding to ligand to see what happens inside the cell. You make a series of mutations and one in particular gives you surprising results: you observe that the mutation that you made in an amino acid that sticks out into the binding pocket actually increases the protein’s affinity for the ligand. Give a molecular explanation for these results

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A. You are performing experiments with your protein of interest and its ligand. You are attempting t...

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