The cities of Portland, Oregon, and Minneapolis, Minnesota, are at about the same latitude, but Minneapolis has much hotter summers and much colder winters than Portland does. Why? (Portland is near the Pacific Ocean; Minneapolis is near a number of large lakes.)

The ocean is so large that it has a highly moderating influence on temperature.

Explanation:

enzyme active site and substrate specificity

enzymes bind with chemical reactants called substrates. there may be one or more substrates for each type of enzyme, depending on the particular chemical reaction. in some reactions, a single-reactant substrate is broken down into multiple products