Biology, 28.02.2020 21:18 lclaudettecarte4720
HER2 is a receptor tyrosine kinase. In 30 percent of human breast cancers, HER2 is permanently activated, resulting in an unregulated cell division. Lapatinib, a drug used to treat breast cancer, inhibits HER2 receptor tyrosine kinase autophosphorylation (the process by which the receptor adds phosphates onto itself), thus reducing tumor growth by 50 percent. Besides autophosphorylation, which of the following steps would be inhibited by Lapatinib?
a. Signaling molecule binding, dimerization, and the downstream cellular response.
b. Dimerization, and the downstream cellular response.
c. The downstream cellular response.
d. Phosphatase activity, dimerization, and the downstream cellular response.
Answers: 1
Biology, 22.06.2019 03:30, masonorourke
Which group of algae is characterized by unicellular organisms and includes some members that would be better classified as zooflagellates? euglenophytes red algae sporozoans green algae
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Biology, 22.06.2019 06:30, jadalysrodriguez
Photosynthesis uses co2 and cellular respiration produces co2. we call the point when the two processes are in balance--when there is no net production of co2--the compensation point. how might you limit one of the processes in order to achieve a compensation point?
Answers: 3
Biology, 22.06.2019 08:40, loganlatimer2001
Where does the information about where each transcription factor binds originate?
Answers: 1
HER2 is a receptor tyrosine kinase. In 30 percent of human breast cancers, HER2 is permanently activ...
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