When performing site‑directed mutagenesis to test predictions about which residues are essential for protein function

equal distribution i think.

"1. it should be, it has been for about 20 years, and it's really not much different in the end than breeding animals to have particular traits. there are always concerns about genetically engineered animals/plants affecting the environment in unexpected negative ways, but i can't think of an example where the fears didn't turn out to be baseless.  

first, as you point out, it would be a great advance in pharmacology, to be able to tailor drugs and their doses to me. the pros involve better medical treatment. the cons involve privacy issues like insurance companies denying coverage to people with genetic risk factors. looking at dna markers wouldn't affect the frequency of genetic diseases, but it would allow detection of them earlier. and ok, actually i suppose that if people used this information to avoid having children with genetic diseases, some might decrease in frequency."

the cover letter for a job search includes the skills one has for the particular job. including a cover letter is always a good idea, as it describes the ability to perform a task, and the employer can easily fetch the intention of the job you want to do.  

the cover letter is very important to be included in the job search document. hence, i strongly with the statement.